From Comparative Effectiveness Research to Patient-Centered Outcomes Research: Integrating Emergency Care Goals, Methods, and Priorities

Patient-centered comparative effectiveness research: essential for high-quality care.

Privacy-preserving analytic methods for multisite comparative effectiveness and patient-centered outcomes research.

BACKGROUND For privacy and practical reasons, it is sometimes necessary to minimize sharing of individual-level information in multisite studies. However, individual-level information is often needed to perform more rigorous statistical analysis. OBJECTIVES To compare empirically 3 analytic methods for multisite studies that only require sharing of summary-level information to perform statist...

The Patient-centered Outcomes Research Institute’s Role in Advancing Methods for Patient-centered Outcomes Research

Currently, there is wide-spread recognition that much of health care is insufficiently grounded in evidence as to what works for whom under what circumstances. An important reason for this is that research efforts often do not compare alternative options of health care nor are they sufficiently focused on outcomes that matter to patients. In addition, the methods to conduct research designed to...

The Patient-Centered Outcomes Research Institute (PCORI) national priorities for research and initial research agenda.

THE PATIENT PROTECTION AND AFFORDABLE CARE ACT of 2010 created the Patient-Centered Outcomes Research Institute (PCORI) to fund and promote comparative clinical effectiveness research (CER) that will “assist patients, clinicians, purchasers, and policymakers in making informed health decisions by advancing the quality and relevance of evidence concerning the manner in which diseases, disorders,...

Emergency care research priorities in South Africa.

BACKGROUND Emergency care research is rarely undertaken in low- and middle-income countries. A manageable 'road map' for research in South African (SA) emergency care is needed to address research gaps. OBJECTIVE To identify, collate and prioritise research topics from identified knowledge gaps in emergency care in SA. METHODS Seventy-six individuals were invited to participate in a modifie...